Hydroxide Free Ferrites for Intravascular Use:

Black Blood-Black Bone MR Image Contrast for

Enhanced MR Imaging of

Blood Vessels, Nerve, & Joints
The hydroxide free ferrites developed by Molecular Synthetics are a powerful and widely useful MR Imaging contrast agent acting in very different ways from the currently dominant gadolinium agents and achieving clinically important effects that current contrast agents cannot approach.

The black blood effect on T2 imaging and bright blood on T1 allow for dramatically improved MR angiography that is not affected by flow turbulence - a problem that limits the utility of "pulse sequence" MR Angiography in critical locations around plaques. Rapid high resolution MR vessel images will be useful for cardiovascular applications and for interventional angiography in the MR suite.

These agents also black out marrow and the vascularized portions of bone allowing for "pure joint images" from any angle of view. These will have important uses in orthopedics and neurosurgery.

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